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Symbol Name ID |
Fah
fumarylacetoacetate hydrolase MGI:95482 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatomegaly |
Cirrhosis |
Hepatocellular carcinoma |
| Disease(s) Associated with FAH | |||
| tyrosinemia type I |
| Mouse Phenotypes | liver/biliary system phenotype |
abnormal hepatocyte mitochondrial morphology |
decreased hepatocyte apoptosis |
decreased hepatocyte proliferation |
liver inflammation |
abnormal liver morphology |
abnormal liver lobule morphology |
abnormal hepatocyte morphology |
small liver |
pale liver |
increased liver tumor incidence |
increased hepatocellular carcinoma incidence |
increased hepatoma incidence |
increased liver adenoma incidence |
abnormal liver physiology |
abnormal hepatocyte physiology |
abnormal liver regeneration |
impaired liver regeneration |
jaundice |
liver failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Fahtm1Mgo/Fahtm1Mgo | * | ||||||||||||||||||||
| Fahem1(IMPC)Mbp/Fah+ | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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